Schizoaffective Disorder

Clinical Description

Schizoaffective Disorder is a mental disorder characterized by a major mood episode (either manic or depressive) that co-occurs at the same time with active-phase symptoms of schizophrenia.


Symptoms (Diagnostic Criteria)

  • Uninterrupted period of illness and a mood episode (major depressive or manic) concurrent with the symptoms (Criterion A) of Schizophrenia.
  • Episodes of depression or mania are present for the majority of the total duration of the illness.

Psychotic Symptoms:

  • Delusions
  • Hallucinations
  • Disorganized speech
  • Grossly disorganized or catatonic behavior

Depressive Symptoms:

  • Depressed mood
  • Anhedonia
  • Changes in weight and appetite
  • Insomnia or hypersomnia
  • Psychomotor disturbance
  • Fatigue
  • Impaired concentration or indecisiveness
  • Feeling worthless or excessive/inappropriate guilt
  • Recurrent thoughts of death or suicide

Manic Symptoms:

  • Inflated self-esteem
  • Decreased need for sleep
  • More talkative than usual
  • Flight of ideas
  • Distractibility
  • Increased goal-directed activity and psychomotor agitation
  • Risk-taking activities

Negative Symptoms:

  • Flat affect: Lack of emotional response or expression
  • Avolition: Lack of motivation or interest in self-initiated purposeful activities (apathy)
  • Anhedonia: Decreased ability to experience pleasure
  • Asociality: Lack of interest in social interactions, activities, or relationships
  • Alogia: Diminished speech output, or slow or delayed responses
  • Anergia: Continual feeling of tiredness, lack of energy, or sleepiness
  • Attention impairment

Duration

  • Delusions or hallucinations have been present for 2 weeks in the absence of a major mood episode (depressive or manic) during the lifetime duration of the illness.

Age Onset and Age Requirement

  • Typically emerge in late teens or early adulthood.

Treatments

  • Medication: Antipsychotics, antidepressants, mood stabilizers.
  • Psychotherapy: Cognitive Behavioral Therapy (CBT), individual psychotherapy, social skills training.
  • Psychosocial support: Family interventions, vocational rehabilitation, supported employment, self-help groups.
  • Electroconvulsive Therapy (ECT)